Observational studies have reported high comorbidity between obesity and severe COVID-19.The aim of this study is to explore whether genetic factors are involved in the co-occurrence of the two traits.Based on the available genome-wide association studies (GWAS) summary statistics, we explored the genetic layer cake chardonnay 2020 correlation and
Ruptured Second Trimester Ectopic Tubal Pregnancy: Case Report
Ectopic pregnancy (EP) is one of the leading causes of maternal mortality.Its frequency in Pakistan is 1:13 pregnancy.1 Tubal igora vibrance 4-99 ectopic often becomes symptomatic in first trimester by eroding the tubal wall and causing hemorrhage and shock.It is very rare for an ectopic to progress into second trimester and remain asymptomatic2.We
Nanocrystal-Based Topical Gels for Improving Wound Healing Efficacy of Curcumin
Topical curcumin shows poor local availability because of its low aqueous solubility and inadequate tissue absorption.Curcumin nanocrystals were prepared by sonoprecipitation followed by lyophilization to improve surface area and solubility.The formulation was optimized by the Design of Experiment (DoE) approach.The nanocrystals were characterized
Factors Affecting Accuracy of Data Abstracted from Medical Records.
Medical record abstraction (MRA) is often cited as a significant source of error in research data, yet MRA methodology has rarely been the subject of investigation.Lack of a common framework has hindered application of the extant literature in practice, and, until now, there were no evidence-based guidelines for ensuring data quality in MRA.We aime
Recent Advancements of Nanotechnology-Based Strategies for Overcoming Tumor Microenvironment Hypoxia
Hypoxia is a typical characteristic of most solid malignancies, which has multiple effects on malignant phenotypes and biological behaviors of tumors including epithelial-mesenchymal-transition (EMT), invasion, migration, metastasis, autophagy, stem cell maintenance, pathological angiogenesis, drug 330 gph filter pump resistance, and immunosuppress